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The diagnosis of CSF infection can be made based on clinical signs of meningitis, septicemia, or meningoencephalitis with typical clinical and laboratory findings. In the present case, the patient was febrile, had pain and the characteristic radiologic findings of both the vertebrae were supportive. We performed CSF analysis and microbiological studies in addition to the imaging studies to make the diagnosis. An early diagnosis is important as it will help in starting timely and effective treatment. The recommended initial treatment involves the use of a combination of antibiotics. The antibiotic treatment should be tailored to the organism isolated from the CSF. However, there is no standard regimen for the treatment of community-acquired bacterial meningitis due to *S. pseudintermedius*. The appropriate empiric therapy should be chosen based on the symptoms and clinical manifestations. The choice of antibiotic therapy should be based on the sensitivity pattern of the organism. In our cases, all of the organisms were sensitive to glycopeptides.

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