When WMIC starts to scan the disk drives of your computer for their serial numbers, it will probably try to read the manufacturer-specific CD-ROM as a disk drive. To make sure that you're in the right place, and that the CD-ROM is booting before Windows starts, open a console window and boot up the computer with the CD in the drive. Shortly after Windows starts, the WMIC command "'wmic logicaldisk get DeviceID'" should show you the disk drive ID. If not, the software was at fault. Check that the CD is installed and connected correctly.
You have to make sure you're "beefing up" the WMI Management install as much as possible. Many components of the WMI implementation are loaded by default, so you might not realize that you're out of date. Here's how to get your WMI install up to date. You can use this information for many purposes, including troubleshooting, by installing a copy of Windows for free, as discussed next.
While some interfaces at the hardware and firmware level of the board itself might not be reconfigured, upstream vendors can forget to add vendor-specific information to their drivers and WMI events. That's what happened with the disk drive serial numbers, which were identified as being under the "Microsoft Management Objects" or MOM part of the WMI unload command. Even if a WMI event or event log shows the correct new serial number, don't take that at face value, because it's not up to date. d2c66b5586